A volume that will provide a comprehensive and up-to-date review on the
potential of peptides and proteins from animal venoms as human therapeutics.
Topics covered will include: the evolution and ecology of venomous animals; the
chemistry and structural biology of animal venoms; venom-based drug discovery:
proteomic and transcriptomic approaches; bioassays, high-throughput screening
methods and target identification; reptile, cone snail, scorpion, spider-venom
peptides and exotic venoms as a platform for drug development; selected case
study examples such as Prialt(R) and Xen2174, exenatide and ShK; the development
of venom natriuretic peptides for treating congestive heart failure; engineering
venom peptides to improve their stability and bioactivity and manufacturing of
venom-derived therapeutic peptides,