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Product Specifications
Book Summary
A volume that will provide a comprehensive and up-to-date review on the
potential of peptides and proteins from animal venoms as human therapeutics.
Topics covered will include: the evolution and ecology of venomous animals; the
chemistry and structural biology of animal venoms; venom-based drug discovery:
proteomic and transcriptomic approaches; bioassays, high-throughput screening
methods and target identification; reptile, cone snail, scorpion, spider-venom
peptides and exotic venoms as a platform for drug development; selected case
study examples such as Prialt(R) and Xen2174, exenatide and ShK; the development
of venom natriuretic peptides for treating congestive heart failure; engineering
venom peptides to improve their stability and bioactivity and manufacturing of
venom-derived therapeutic peptides,
ISBN-13
9781849736633
Language
English
Binding
Hard Bound
Publisher
Royal Society of Chemistry
Publishing Date
2015-02-10
Total Pages
320
Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics (RSC Drug Discovery)
A volume that will provide a comprehensive and up-to-date review on the
potential of peptides and proteins from animal venoms as human therapeutics.
Topics covered will include: the evolution and ecology of venomous animals; the
chemistry and structural biology of animal venoms; venom-based drug discovery:
proteomic and transcriptomic approaches; bioassays, high-throughput screening
methods and target identification; reptile, cone snail, scorpion, spider-venom
peptides and exotic venoms as a platform for drug development; selected case
study examples such as Prialt(R) and Xen2174, exenatide and ShK; the development
of venom natriuretic peptides for treating congestive heart failure; engineering
venom peptides to improve their stability and bioactivity and manufacturing of
venom-derived therapeutic peptides,