This book not only surveys the whole arena of novel anticancer drug targets, but
also presents a wide-ranging selection of cutting-edge techniques currently
being applied throughout novel antitumor drug discovery and development. The
methods are applied to experiments involving such topics as immunotherapy,
angiogenesis, cancer metastasis, the cell cycle, signal transduction inhibitors,
apoptosis, antibodies, antisense molecules, microarray gene expression, flow
cytometry, and PET imaging for cancer target validation. There are also proven
methods for the preclinical identification of drug targets and for target
validation during the clinical trials of novel agents.