The issue of male germ line mutagenesis and the effects on developmental defects
in the next generation has become increasingly high profile over recent years.
Mutations are thought to be becoming more prevalent as a result of: exposure to
chemicals in the environment, anti cancer regimes that use genotoxic agents and
assisted conception techniques. In addition to the increasing frequency of
mutations in the general population, attention is also being given to the
effects of epigenetic events on future generations. Male-mediated Developmental
Toxicity discusses these issues comprehensively and includes further analysis on
the fundamental mechanisms of mutations. With both clinical and experimental
sections, written by leading experts in