This book integrates recent advances in molecular and cell biology of
hematopoietic stem cells (HSC) with developments in clinical research in stem
cell-based therapy-providing an up-to-date review of novel cytokines and
cellular components; animal models; cell preparation, selection, and collection;
minimal residual disease and purging; expansion of progenitor cells; allogeneic
and autologous transplantation; cellular gene and immunotherapy; and more.
Examines key areas for treatment with HSC, including ambulatory care and
monitoring, regimen-related toxicities, immunodeficiency and immunization,
infection, chronic graft-versus-host and disease, secondary malignancies, and
long-term quality of life.
Covering stem cell pool regulation and the complex interplay of extrinsic and
intrinsic events, Hematopoietic Stem Cell Transplantation
summarizes current understanding