This volume supplements Volumes 63, 64, 87, and 249 of Methods in Enzymology.
These volumes provide a basic source for the quantitative interpretation of
enzyme rate data and the analysis of enzyme catalysis. Among the major topics
covered are Engergetic Coupling in Enzymatic Reactions, Intermediates and
Complexes in Catalysis, Detection and Properties of Low Barrier Hydrogen Bonds,
Transition State Determination, and Inhibitors.
The critically acclaimed laboratory standard for more than forty years, Methods
in Enzymology is one of the most highly respected publications in the field of
biochemistry. Since 1955, each volume has been eagerly awaited, frequently
consulted, and praised by researchers and reviewers alike. Now with more