This book brings together drug design practitioners, all leaders in their field,
who are actively advancing the field of quantitative methods to guide drug
discovery, from structure-based design to empirical statistical models - from
rule-based approaches to toxicology to the fields of bioinformatics and systems
biology. The aim of the book is to show how various facets of the drug discovery
process can be addressed in a quantitative fashion (ie: numerical analysis to
enable robust predictions to be made). Each chapter includes a brief review of
the topic showing the historical development of quantitative approaches, a
survey/summary of the current state-of-the-art, a selection of well chosen
examples with