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Book Summary
This collection of readily reproducible techniques for repairing mammalian DNA
contains fourteen entirely new chapters and many extensively revised chapters.
The methods presented cover cytogenetic analysis, measuring the cellular
response to ionizing radiation, detecting single-strand (nicks) and
double-strand DNA breaks, detecting the presence of "adducted" bases in DNA, and
preparing mismatch repair (MMR) plasmid substrates. Among the highlights are
excellent coverage of both base excision repair (BER) and nucleotide excision
repair (NER), useful assays for identifying and quantifying UV-induced DNA
lesions and DNA breakage, gene therapy, environmental mutagenesis and cancer,
and gene targeting.
- ISBN-13
- 9781588295132
- Language
- English
- Binding
- Hard Bound
- Publisher
- cbspd
- Publishing Date
- 2005-10-01
- Product Edition
- 2nd Edition
- Total Pages
- 516
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Product Specifications
Book Summary
This collection of readily reproducible techniques for repairing mammalian DNA
contains fourteen entirely new chapters and many extensively revised chapters.
The methods presented cover cytogenetic analysis, measuring the cellular
response to ionizing radiation, detecting single-strand (nicks) and
double-strand DNA breaks, detecting the presence of "adducted" bases in DNA, and
preparing mismatch repair (MMR) plasmid substrates. Among the highlights are
excellent coverage of both base excision repair (BER) and nucleotide excision
repair (NER), useful assays for identifying and quantifying UV-induced DNA
lesions and DNA breakage, gene therapy, environmental mutagenesis and cancer,
and gene targeting.
Book Specifications
- ISBN-13
- 9781588295132
- Language
- English
- Binding
- Hard Bound
- Publisher
- cbspd
- Publishing Date
- 2005-10-01
- Product Edition
- 2nd Edition
- Total Pages
- 516