Many experimental methods and mathematical modeling approaches rooted in
disciplines outside of toxicology can be effectively applied to estimating
dermal absorption. Dermal Absorption Models in Toxicology and Pharmacology
explores current approaches and techniques that can be used to quantify dermal
absorption with endpoints useful in both toxicology and pharmacology.
The book begins with a review of basic principles and the in vitro and in vivo
experimental approaches available for assessing dermal absorption of drugs and
chemicals. This is followed by coverage of mathematical or in silico models for
quantitating percutaneous absorption and the applications of these techniques to
the risk assessment process. The remainder of the book