The first edition of Comprehensive Medicinal Chemistry was published in 1990 and
was very well received. Comprehensive Medicinal Chemistry II is much more than a
simple updating of the contents of the first edition. Completely revised and
expanded, this new edition has been refocused to reflect the significant
developments and changes over the past decade in genomics, proteomics,
bioinformatics, combinatorial chemistry, high-throughput screening and
pharmacology, and more. The content comprises the most up-to-date, authoritative
and comprehensive reference text on contemporary medicinal chemistry and drug
research, covering major therapeutic classes and targets, research strategy and
organisation, high-throughput technologies, computer-assisted design, ADME and
selected case histories. It is this coverage of