Comprehensive Biomarker Discovery and Validation for Clinical Application
provides the reader with an extensive introduction into all aspects of
proteomics biomarker discovery, validation and development. It discusses the
current status of science and technology, its limitations, bottlenecks as well
as future development trends to improve the success rate of translating
biomarker discovery into useful clinical tests. The most important feature of
the book is to provide an overview of current technologies and the challenges
encountered during biomarker discovery and validation, such as patient
selection, sample handling, data processing, statistical analysis and
registration and approval of validated biomarkers through European and US
regulatory authorities. The authors introduce the reader to