Concerns about the adverse effects of chemicals present in the environment have
created a need for better systems to assess their potential consequences on
human health. One potential solution is the versatile and state-of-the-art Comet
assay. Simple, sensitive, rapid and visual, this modern toxicological method
allows quantitative and qualitative assessment of DNA damage in single cells.
This assay is used in diverse fields ranging from clinical applications, human
monitoring and environmental toxicology through to genetic toxicity testing.
This updated and revised edition of The Comet Assay in Toxicology provides the
latest information on this important tool. It addresses, in-depth, the different
protocols, statistical analyses and applications used worldwide.