About the Book: Bacterialartificial Chromosomes
This book focuses on the numerous applications of Bacterial Artificial
Chromosomes (BACs) in a variety of studies. The topics reviewed range from using
BAC libraries as resources for marsupial and monotreme gene mapping and
comparative genomic studies, to using BACs as vehicles for maintaining the large
infectious DNA genomes of viruses.
The large size of the insert DNA in BACs and the ease of engineering mutations
in that DNA within the bacterial host, allowed manipulating the BAC-viral DNA of
Varicella-Zoster Virus.
Other reviews include the maintenance and suitable expression of foreign genes
from a Baculovirus genome, including protein complexes, from