The demands for green and sustainable synthetic methods in the fields of
healthcare and fine chemicals, combined with the pressure to produce these
substances expeditiously and in an environmentally benign fashion, pose
significant challenges to the synthetic chemical community. Green chemistry can
avoid pollution by utilizing techniques that are environmentally friendly by
design and one of the best green techniques is the use of microwave (MW)
assisted aqueous synthetic protocols. Fusing MW technique with water (as a
benign reaction medium) can offer an extraordinary synergistic effect with
greater potential than these two individual components in isolation. Selective
microwave heating can be exploited to develop a high yield protocol