Antisense technology is the ability to manipulate gene expression within
mammalian cells providing powerful experimental approaches for the study of gene
function and gene regulation. For example, methods which inhibit gene expression
permit studies probing the normal function of a specific product within a cell.
Such methodology can be used in many disciplines such as pharmacology, oncology,
genetics, cell biology, developmental biology, molecular biology, biochemistry,
and neurosciences. This volume will be a truly important tool in
biomedically-oriented research.
The critically acclaimed laboratory standard for more than forty years, Methods
in Enzymology is one of the most highly respected publications in the field of
biochemistry. Since 1955, each volume has